Chimeric Primates: Embryonic Stem Cells Need Not Apply
نویسندگان
چکیده
منابع مشابه
Chimeric Primates: Embryonic Stem Cells Need Not Apply
In this issue, Tachibana et al. report the generation of the first chimeras from a nonhuman primate, the rhesus monkey. Unlike mice, rhesus chimeras fail to form when embryonic stem cells are injected into blastocysts. Instead, chimera formation is achieved by aggregation of several four-cell embryos.
متن کاملDiagnostics Need Not Apply
ideas themselves are un-patentable "as they are the basic tools of scientific and technological work,"58 useful applications of these tools may be patent-eligible. A claim to a process that uses a natural law must "also contain other elements or a combination of elements, sometimes referred to as an 'inventive concept,' sufficient to ensure that the patent in practice amounts to 55 See supra no...
متن کاملMethods to Generate Chimeric Mice from Embryonic Stem Cells
A chimera is an animal that has two or more populations of genetically distinct cells that originated in different embryos, fetuses, or individuals of the same or different species. During recent decades, embryos, the inner cell mass (ICM), teratocarcinoma stem cells, embryonal carcinoma stem cells, embryonic stem (ES) cells (ESCs), primordial germ cells, spermatogonial stem cells, extraembryon...
متن کاملDifferentiation of Mouse Embryonic Stem Cells into Hematopoietic Cells
Purpose: Differentiation of Mouse embryonicstem cells into Hematopoietic cells. Materials and Methods: In this study, we used EB formation system for Hematopoietic differentiation of mouse embryonic stem cell (Royan B1) in suspension culture. EBs cultured in medium with Hematopoietic inducer cytokines (SCF, TPO, GMCSF, IL3, Flt3 and EPO) .presence of hematopoietic differentiated cell assessed ...
متن کاملComparing the Expression Levels of Alkaline Phosphatase, Gfra1, Lin28, and Sall4 Genes in Embryonic Stem Cells, Spermatogonial Stem Cells, and Embryonic Stem-Like Cells in Mice
Background and purpose: Spermatogenesis is a well-organized process that is influenced by a variety of factors. Alkaline phosphatase, and Gfra1, Lin28, and Sall4 genes are among the key players in this interconnected process. This study aimed to investigate the expression levels of Gfra1, Lin28, and Sall4 genes in embryonic, spermatogonial, and embryonic stem-like (ES-like) cells in mice. Mate...
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ژورنال
عنوان ژورنال: Cell
سال: 2012
ISSN: 0092-8674
DOI: 10.1016/j.cell.2011.12.016